Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2070 |
Agerafenib
RXDX-105,CEP 32496,CEP-32496,CEP32496 |
Raf; c-RET; Bcr-Abl; PDGFR; Src; c-Kit | Angiogenesis; Apoptosis; Cytoskeletal Signaling; MAPK; Tyrosine Kinase/Adaptors |
Agerafenib (CEP32496) 是口服高效的 BRAFV600E 抑制剂,Kd 为 14 nM。 | |||
T14928 |
Agerafenib hydrochloride
RXDX-105 hydrochloride,CEP-32496 (hydrochloride) |
c-RET; c-Kit | Apoptosis; Tyrosine Kinase/Adaptors |
Agerafenib hydrochloride is a highly potent inhibitor of BRAFV600E (Kd: 14 nM). |